研究業績

2024年

  1. Fukumura K, Masuda A, Takeda J, Nagano O, Saya H, Ohno K, Mayeda A.
    RNPS1 in PSAP complex controls periodic pre-mRNA splicing over the cell cycle.
    iScience. (2024) in press
  2. Zhang J, Fu L, Wang H, Yonemura A, Semba T, Yasuda-Yoshihara N, Nishimura A, Tajiri T, Tong Y, Yasuda T, Uchihara T, Yamazaki M, Okamoto Y, Yamasaki J, Nagano O, Baba H, Ishimoto T.
    RAC1-mediated integrin alpha-6 expression in E-cadherin-deficient gastric cancer cells promotes interactions with the stroma and peritoneal dissemination.
    Cancer Lett. (2024) Jun 1;591:216901. DOI: 10.1016/j.canlet.2024.216901
  3. Kasai S, Tamai M, Sugihara E, Oishi N, Hinata K, Akahane K, Goi K, Hata Y, Kondo T, Mitsui T, Tanaka M, Inukai T.
    In utero tumor development and identification of CTNNB1 mutation in a newborn case of ossifying renal tumor of infancy.
    Pediatr Blood Cancer. (2024) Apr;71(4):e30868. DOI: 10.1002/pbc.30868
  4. Yonemura A, Semba T, Zhang J, Fan Y, Yasuda-Yoshihara N, Wang H, Uchihara T, Yasuda T, Nishimura A, Fu L, Hu X, Wei F, Kitamura F, Akiyama T, Yamashita K, Eto K, Iwagami S, Iwatsuki M, Miyamoto Y, Matsusaki K, Yamasaki J, Nagano O, Saya H, Song S, Tan P, Baba H, Ajani JA, Ishimoto T.
    Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment.
    Cell Rep. (2024) Jan 23;43(1):113613. DOI: 10.1016/j.celrep.2023.113613

2023年

  1. Fukumura K, Sperotto L, Seuß S, Kang HS, Yoshimoto R, Sattler M, Mayeda A.
    SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns.
    Cell Rep. (2023) Dec 26;42(12):113534. DOI: 10.1016/j.celrep.2023.113534
  2. Nagamine H, Yashiro M, Yoshimoto N, Izumi M, Sugimoto A, Nakahama K, Ogawa K, Matsumoto Y, Sawa K, Tani Y, Kaneda H, Mitsuoka S, Yamada K, Watanabe T, Aasai K, Fukumura K, Mayeda A, Kawaguchi T.
    RBM17 Expression Is Associated With the Efficacy of ICI Monotherapy in NSCLC With Low PD-L1 Expression.
    Anticancer Res. (2023) Oct;43(10):4663-4672. DOI: 10.21873/anticanres
  3. Kitamura F, Semba T, Yasuda-Yoshihara N, Yamada K, Nishimura A, Yamasaki J, Nagano O, Yasuda T, Yonemura A, Tong Y, Wang H, Akiyama T, Matsumura K, Uemura N, Itoyama R, Bu L, Fu L, Hu X, Wei F, Mima K, Imai K, Hayashi H, Yamashita YI, Miyamoto Y, Baba H, Ishimoto T.
    Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer.
    JCI Insight. (2023) Oct 23;8(20):e163022. DOI: 10.1172/jci.insight.163022
  4. Hattori A, Takamatsu-Ichihara E, Yamamoto Y, Fujita S, Yamagata K, Katsumoto T, Machida Y, Shinohara H, Murakami R, Kitabayashi I.
    Genetic and chemical targeting of the ATPase complex TIP48 and 49 impairs acute myeloid leukemia.
    Leukemia. (2023) Sep;37(9):1812-1829. DOI: 10.1038/s41375-023-01971-4
  5. Sugimoto A, Watanabe T, Matsuoka K, Okuno Y, Yanagi Y, Narita Y, Mabuchi S, Nobusue H, Sugihara E, Hirayama M, Ide T, Onouchi T, Sato Y, Kanda T, Saya H, Iwatani Y, Kimura H, Murata T.
    Growth Transformation of B Cells by Epstein-Barr Virus Requires IMPDH2 Induction and Nucleolar Hypertrophy.
    Microbiol Spectr. (2023) Aug 17;11(4):e0044023. DOI: 10.1128/spectrum.00440-23
  6. Ichihara H, Yamada M, Kohara M, Hirakawa H, Ghelfi A, Tamura T, Nakaya A, Nakamura Y, Shirasawa S, Yamashita S, Toda Y, Harada D, Fujishiro T, Komaki A, Fawcett JA, Sugihara E, Tabata S, Isobe SN.
    Plant GARDEN: a portal website for cross-searching between different types of genomic and genetic resources in a wide variety of plant species.
    BMC Plant Biol. (2023) Aug 12;23(1):391. DOI: 10.1186/s12870-023-04392-8
  7. Wei F, Uchihara T, Yonemura A, Yasuda-Yoshihara N, Yasuda T, Semba T, Fukuda M, Akiyama T, Kitamura F, Bu L, Hu X, Fu L, Zhang J, Kariya R, Yamasaki J, Aihara K, Yamashita K, Nagano O, Okada S, Baba H, Ishimoto T.
    A novel tdTomato transgenic mouse model to visualize FAP-positive cancer-associated fibroblasts.
    FEBS J. (2023) May;290(10):2604-2615. DOI: 10.1111/febs.16712
  8. Fan Y, Li Y, Yao X, Jin J, Scott A, Liu B, Wang S, Huo L, Wang Y, Wang R, Pool Pizzi M, Ma L, Shao S, Sewastjanow-Silva M, Waters R, Chatterjee D, Liu B, Shanbhag N, Peng G, Calin GA, Mazur PK, Hanash SM, Ishizawa J, Hirata Y, Nagano O, Wang Z, Wang L, Xian W, McKeon F, Ajani JA, Song S.
    Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment.
    Gut. (2023) Apr;72(4):624-637. DOI: 10.1136/gutjnl-2021-326581
  9. Nukaya T, Sumitomo M, Sugihara E, Takeda M, Nohara S, Tanishima S, Takenaka M, Zennami K, Takahara K, Shiroki R, Saya H.
    Estimating copy number to determine BRCA2 deletion status and to expect prognosis in localized prostate cancer.
    Cancer Med. (2023) Apr;12(7):8154-8165. DOI: 10.1002/cam4.5617
  10. Akiyama T, Yasuda T, Uchihara T, Yasuda-Yoshihara N, Tan BJY, Yonemura A, Semba T, Yamasaki J, Komohara Y, Ohnishi K, Wei F, Fu L, Zhang J, Kitamura F, Yamashita K, Eto K, Iwagami S, Tsukamoto H, Umemoto T, Masuda M, Nagano O, Satou Y, Saya H, Tan P, Baba H, Ishimoto T.
    Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti-PD-1 Immunotherapy in Fibrotic Tumors.
    Cancer Res. (2023) Mar 2;83(5):753-770. DOI: 10.1158/0008-5472.CAN-22-1890
  11. Mariya T, Shichiri Y, Sugimoto T, Kawamura R, Miyai S, Inagaki H, Sugihara E, Ikeda K, Baba T, Ishikawa A, Ammae M, Nakaoka Y, Saito T, Sakurai A, Kurahashi H.
    Clinical application of long-read nanopore sequencing in a preimplantation genetic testing pre-clinical workup to identify the junction for complex Xq chromosome rearrangement-related disease.
    Prenat Diagn. (2023) Mar;43(3):304-313. DOI: 10.1002/pd.6334
  12. Ito J, Yamagata K, Shinohara H, Shima Y, Katsumoto T, Aikawa Y, Kitabayashi I.
    Dual inhibition of EZH1/2 induces cell cycle arrest of B cell acute lymphoblastic leukemia cells through upregulation of CDKN1C and TP53INP1.
    Int J Hematol. (2023) Jan;117(1):78-89. DOI: 10.1007/s12185-022-03469-8

2022年

  1. Shimizu T, Sugihara E, Takeshima H, Nobusue H, Yamaguchi R, Yamaguchi-Iwai S, Fukuchi Y, Ushijima T, Muto A, Saya H.
    Depletion of R270C Mutant p53 in Osteosarcoma Attenuates Cell Growth but Does Not Prevent Invasion and Metastasis In Vivo.
    Cells. (2022) Nov 15;11(22):3614. DOI: 10.3390/cells11223614
  2. Nakagawa M, Sekimizu M, Endo M, Kobayashi E, Iwata S, Fukushima S, Yoshida A, Kitabayashi I, Ichikawa H, Kawai A, Nakatani F.
    Prognostic impact of IDH mutations in chondrosarcoma.
    J Orthop Sci. (2022) Nov;27(6):1315-1322. DOI: 10.1016/j.jos.2021.07.024
  3. Katsumoto T, Ogawara Y, Yamagata K, Aikawa Y, Goitsuka R, Nakamura T, Kitabayashi I.
    MOZ is critical for the development of MOZ/MLL fusion-induced leukemia through regulation of Hoxa9/Meis1 expression.
    Blood Adv. (2022) Oct 11;6(19):5527-5537. DOI: 10.1182/bloodadvances.2020003490
  4. Ueno S, Sudo T, Saya H, Sugihara E.
    Pigment epithelium-derived factor promotes peritoneal dissemination of ovarian cancer through induction of immunosuppressive macrophages.
    Commun Biol. (2022) Sep 2;5(1):904. DOI: 10.1038/s42003-022-03837-4
  5. Shinohara H, Sawado R, Nakagawa M, Hattori A, Yamagata K, Tauchi K, Ito J, Kuwahara Y, Okuda T, Ogawa C, Kitabayashi I.
    Dual targeting of EZH1 and EZH2 for the treatment of malignant rhabdoid tumors.
    Mol Ther Oncolytics. (2022) Sep 19;27:14-25. DOI: 10.1016/j.omto.2022.09.006
  6. Uetaki M, Onishi N, Oki Y, Shimizu T, Sugihara E, Sampetrean O, Watanabe T, Yanagi H, Suda K, Fujii H, Kano K, Saya H, Nobusue H.
    Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis.
    Mol Biol Cell. (2022) Aug 1;33(9):ar78. DOI: 10.1091/mbc.E21-12-0609
  7. Shichino S, Ueha S, Hashimoto S, Ogawa T, Aoki H, Wu B, Chen CY, Kitabatake M, Ouji-Sageshima N, Sawabata N, Kawaguchi T, Okayama T, Sugihara E, Hontsu S, Ito T, Iwata Y, Wada T, Ikeo K, Sato TA, Matsushima K.
    TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq.
    Commun Biol. (2022) Jun 27;5(1):602. DOI: 10.1038/s42003-022-03536-0
  8. Mariya T, Kato T, Sugimoto T, Miyai S, Inagaki H, Ohye T, Sugihara E, Muramatsu Y, Mizuno S, Kurahashi H.
    Target enrichment long-read sequencing with adaptive sampling can determine the structure of the small supernumerary marker chromosomes.
    J Hum Genet. (2022) Jun;67(6):363-368. DOI: 10.1038/s10038-021-01004-x
  9. Mizuno S, Seishima R, Yamasaki J, Hattori K, Ogiri M, Matsui S, Shigeta K, Okabayashi K, Nagano O, Li L, Kitagawa Y.
    Angiopoietin-like 4 promotes glucose metabolism by regulating glucose transporter expression in colorectal cancer.
    J Cancer Res Clin Oncol. (2022) Jun;148(6):1351-1361. DOI: 10.1007/s00432-022-03960-z
  10. Nakagawa M, Yamaguchi M, Endo M, Machida Y, Hattori A, Tanzawa F, Tsutsumi S, Kitabayashi I, Kawai A, Nakatani F.
    Clinical usefulness of 2-hydroxyglutarate as a biomarker in IDH-mutant chondrosarcoma.
    J Bone Oncol. (2022) Apr 16;34:100430. DOI: 10.1016/j.jbo.2022.100430
  11. Anh LPH, Nishimura K, Kuno A, Linh NT, Kato T, Ohtaka M, Nakanishi M, Sugihara E, Sato TA, Hayashi Y, Fukuda A, Hisatake K.
    Downregulation of Odd-Skipped Related 2, a Novel Regulator of Epithelial-Mesenchymal Transition, Enables Efficient Somatic Cell Reprogramming.
    Stem Cells. (2022) Apr 29;40(4):397-410. DOI: 10.1093/stmcls/sxac012
  12. Yamasaki J, Hirata Y, Otsuki Y, Suina K, Saito Y, Masuda K, Okazaki S, Ishimoto T, Saya H, Nagano O.
    MEK inhibition suppresses metastatic progression of KRAS-mutated gastric cancer.
    Cancer Sci. (2022) Mar;113(3):916-925. DOI: 10.1111/cas.15244
  13. Tsuchihashi K, Hirata Y, Yamasaki J, Suina K, Tanoue K, Yae T, Masuda K, Baba E, Akashi K, Kitagawa Y, Saya H, Nagano O.
    Presence of spontaneous epithelial-mesenchymal plasticity in esophageal cancer.
    Biochem Biophys Rep. (2022) Mar 19;30:101246. DOI: 10.1016/j.bbrep.2022.101246
  14. Oki Y, Hagiwara R, Matsumaru T, Kano K.
    Effect of volatile fatty acids on adipocyte differentiation in bovine dedifferentiated fat (DFAT) cells in vitro.
    Genes Cells. (2022) Jan;27(1):5-13. DOI: 10.1111/gtc.12903
  15. Aizawa S, Nishimura K, Mondejar GS, Kumar A, Bui PL, Tran YTH, Kuno A, Muratani M, Kobayashi S, Nabekura T, Shibuya A, Sugihara E, Sato TA, Fukuda A, Hayashi Y, Hisatake K. Early reactivation of clustered genes on the inactive X chromosome during somatic cell reprogramming.
    Stem Cell Reports. (2022) Jan 11;17(1):53-67. DOI: 10.1016/j.stemcr.2021.11.008

2021年

  1. Daisuke H, Kato H, Fukumura K, Mayeda A, Miyagi Y, Seiki M, Koshikawa N.
    Novel LAMC2 fusion protein has tumor-promoting properties in ovarian carcinoma.
    Cancer Sci. (2021) Dec;112(12):4957-4967. DOI: 10.1111/cas.15149
  2. Shimizu T, Kimura K, Sugihara E, Yamaguchi-Iwai S, Nobusue H, Sampetrean O, Otsuki Y, Fukuchi Y, Saitoh K, Kato K, Soga T, Muto A, Saya H.
    MEK inhibition preferentially suppresses anchorage-independent growth in osteosarcoma cells and decreases tumors in vivo.
    J Orthop Res. (2021) Dec;39(12):2732-2743. DOI: 10.1002/jor.25023
  3. Borisova E, Nishimura K, An Y, Takami M, Li J, Song D, Matsuo-Takasaki M, Luijkx D, Aizawa S, Kuno A, Sugihara E, Sato TA, Yumoto F, Terada T, Hisatake K, Hayashi Y.
    Structurally-discovered KLF4 variants accelerate and stabilize reprogramming to pluripotency.
    iScience. (2021) Dec 14;25(1):103525. DOI: 10.1016/j.isci.2021.103525
  4. Fukumura K, Venables JP, Mayeda A.
    SPF45/RBM17-dependent splicing and multidrug resistance to cancer chemotherapy.
    Mol Cell Oncol. (2021) Nov 15;8(6):1996318. DOI: 10.1080/23723556.2021.1996318
  5. Yamagata K, Shino M, Aikawa Y, Fujita S, Kitabayashi I.
    Tip60 activates Hoxa9 and Meis1 expression through acetylation of H2A.Z, promoting MLL-AF10 and MLL-ENL acute myeloid leukemia.
    Leukemia. (2021) Oct;35(10):2840-2853. DOI: 10.1038/s41375-021-01244-y
  6. Fukumura K, Yoshimoto R, Sperotto L, Kang HS, Hirose T, Inoue K, Sattler M, Mayeda A.
    SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns.
    Nat Commun. (2021) Aug 13;12(1):4910. DOI: 10.1038/s41467-021-24879-y
  7. Mizuno M, Khaledian B, Maeda M, Hayashi T, Mizuno S, Munetsuna E, Watanabe T, Kono S, Okada S, Suzuki M, Takao S, Minami H, Asai N, Sugiyama F, Takahashi S, Shimono Y.
    Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction.
    Cancers (Basel). (2021) Aug 23;13(16):4238. DOI: 10.3390/cancers13164238
  8. Kishimoto K, Kanazawa K, Nomura M, Tanaka T, Shigemoto-Kuroda T, Fukui K, Miura K, Kurosawa K, Kawai M, Kato H, Terasaki K, Sakamoto Y, Yamashita Y, Sato I, Tanuma N, Tamai K, Kitabayashi I, Matsuura K, Watanabe T, Yasuda J, Tsuji H, Shima H.
    Ppp6c deficiency accelerates K-rasG12D -induced tongue carcinogenesis.
    Cancer Med. (2021) Jul;10(13):4451-4464. DOI: 10.1002/cam4.3962
  9. Fujii Y, Sato Y, Suzuki H, Kakiuchi N, Yoshizato T, Lenis AT, Maekawa S, Yokoyama A, Takeuchi Y, Inoue Y, Ochi Y, Shiozawa Y, Aoki K, Yoshida K, Kataoka K, Nakagawa MM, Nannya Y, Makishima H, Miyakawa J, Kawai T, Morikawa T, Shiraishi Y, Chiba K, Tanaka H, Nagae G, Sanada M, Sugihara E, Sato TA, Nakagawa T, Fukayama M, Ushiku T, Aburatani H, Miyano S, Coleman JA, Homma Y, Solit DB, Kume H, Ogawa S.
    Molecular classification and diagnostics of upper urinary tract urothelial carcinoma.
    Cancer Cell. (2021) Jun 14;39(6):793-809.e8. DOI: 10.1016/j.ccell.2021.05.008
  10. Kagiyama Y, Fujita S, Shima Y, Yamagata K, Katsumoto T, Nakagawa M, Honma D, Adachi N, Araki K, Kato A, Inaki K, Ono Y, Fukuhara S, Kobayashi Y, Tobinai K, Kitabayashi I.
    CDKN1C-mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib.
    Cancer Sci. (2021) Jun;112(6):2314-2324. DOI: 10.1111/cas.14905
  11. Kasuga A, Semba T, Sato R, Nobusue H, Sugihara E, Takaishi H, Kanai T, Saya H, Arima Y.
    Oncogenic KRAS-expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice.
    Cancer Sci. (2021) May;112(5):1822-1838. DOI: 10.1111/cas.14703

2020年

  1. Fujiwara N, Shibutani S, Sakai Y, Watanabe T, Kitabayashi I, Oshima H, Oshima M, Hoshida H, Akada R, Usui T, Ohama T, Sato K.
    Autophagy regulates levels of tumor suppressor enzyme protein phosphatase 6.
    Cancer Sci. (2020) Dec;111(12):4371-4380. DOI: 10.1111/cas.14662
  2. Yanagi H, Watanabe T, Nishimura T, Hayashi T, Kono S, Tsuchida H, Hirata M, Kijima Y, Takao S, Okada S, Suzuki M, Imaizumi K, Kawada K, Minami H, Gotoh N, Shimono Y.
    Upregulation of S100A10 in metastasized breast cancer stem cells.
    Cancer Sci. (2020) Dec;111(12):4359-4370. DOI: 10.1111/cas.14659
  3. Hagiwara R, Oki Y, Matsumaru T, Ibayashi S, Kano K.
    Generation of metabolically functional hepatocyte-like cells from dedifferentiated fat cells by Foxa2, Hnf4a and Sall1 transduction.
    Genes Cells. (2020) Dec;25(12):811-824. DOI: 10.1111/gtc.12814
  4. Muraoka S, Fukumura K, Hayashi M, Kataoka N, Mayeda A, Kaida D.
    Rbm38 Reduces the Transcription Elongation Defect of the SMEK2 Gene Caused by Splicing Deficiency.
    Int J Mol Sci. (2020) Nov 20;21(22):8799. DOI: 10.3390/ijms21228799
  5. Sugihara E, Hashimoto N, Osuka S, Shimizu T, Ueno S, Okazaki S, Yaguchi T, Kawakami Y, Kosaki K, Sato TA, Okamoto S, Saya H.
    The Inhibitor of Apoptosis Protein Livin Confers Resistance to Fas-Mediated Immune Cytotoxicity in Refractory Lymphoma.
    Cancer Res. (2020) Oct 15;80(20):4439-4450. DOI: 10.1158/0008-5472.CAN-19-3993
  6. Miyamoto R, Okuda H, Kanai A, Takahashi S, Kawamura T, Matsui H, Kitamura T, Kitabayashi I, Inaba T, Yokoyama A.
    Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia.
    Cell Rep. (2020) Sep 29;32(13):108200. DOI: 10.1016/j.celrep.2020.108200
  7. Arima Y, Nobusue H, Saya H.
    Targeting of cancer stem cells by differentiation therapy.
    Cancer Sci. (2020) Aug;111(8):2689-2695. DOI: 10.1111/cas.14504
  8. Ochi Y, Kon A, Sakata T, Nakagawa MM, Nakazawa N, Kakuta M, Kataoka K, Koseki H, Nakayama M, Morishita D, Tsuruyama T, Saiki R, Yoda A, Okuda R, Yoshizato T, Yoshida K, Shiozawa Y, Nannya Y, Kotani S, Kogure Y, Kakiuchi N, Nishimura T, Makishima H, Malcovati L, Yokoyama A, Takeuchi K, Sugihara E, Sato TA, Sanada M, Takaori-Kondo A, Cazzola M, Kengaku M, Miyano S, Shirahige K, Suzuki HI, Ogawa S.
    Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes.
    Cancer Discov. (2020) Jun;10(6):836-853. DOI: 10.1158/2159-8290.CD-19-0982
  9. Funahashi Y, Watanabe T, Kaibuchi K.
    Advances in defining signaling networks for the establishment of neuronal polarity.
    Curr Opin Cell Biol. (2020) Apr; 63: 76-87. DOI: 10.1016/j.ceb.2019.12.009
  10. Kunitomi H, Oki Y, Onishi N, Kano K, Banno K, Aoki D, Saya H, Nobusue H.
    The insulin-PI3K-Rac1 axis contributes to terminal adipocyte differentiation through regulation of actin cytoskeleton dynamics.
    Genes Cells. (2020) Mar;25(3):165-174. DOI: 10.1111/gtc.12747
  11. Machida Y, Nakagawa M, Matsunaga H, Yamaguchi M, Ogawara Y, Shima Y, Yamagata K, Katsumoto T, Hattori A, Itoh M, Seki T, Nishiya Y, Nakamura K, Suzuki K, Imaoka T, Baba D, Suzuki M, Sampetrean O, Saya H, Ichimura K, Kitabayashi I.
    A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model.
    Mol Cancer Ther. (2020) Feb;19(2):375-383. DOI: 10.1158/1535-7163.MCT-18-1349
  12. Otsuki Y, Yamasaki J, Suina K, Okazaki S, Koike N, Saya H, Nagano O.
    Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT-targeted therapy.
    Cancer Sci. (2020) Jan;111(1):127-136. DOI: 10.1111/cas.14224
  13. Kakiuchi N, Yoshida K, Uchino M, Kihara T, Akaki K, Inoue Y, Kawada K, Nagayama S, Yokoyama A, Yamamoto S, Matsuura M, Horimatsu T, Hirano T, Goto N, Takeuchi Y, Ochi Y, Shiozawa Y, Kogure Y, Watatani Y, Fujii Y, Kim SK, Kon A, Kataoka K, Yoshizato T, Nakagawa MM, Yoda A, Nanya Y, Makishima H, Shiraishi Y, Chiba K, Tanaka H, Sanada M, Sugihara E, Sato TA, Maruyama T, Miyoshi H, Taketo MM, Oishi J, Inagaki R, Ueda Y, Okamoto S, Okajima H, Sakai Y, Sakurai T, Haga H, Hirota S, Ikeuchi H, Nakase H, Marusawa H, Chiba T, Takeuchi O, Miyano S, Seno H, Ogawa S.
    Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis.
    Nature. (2020) Jan;577(7789):260-265. DOI: 10.1038/s41586-019-1856-1
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